Table 3.
Simulated Type I Error Rates for Dichotomous Traits[Note]
|
Type I Error Rate atNominal Significance Level |
||||
| Frequencyof Allele A,Sample Size,and Statistic | .1 | .05 | .01 | .001 |
| p=.1: | ||||
| n=100: | ||||
| ΛNew | .0694 | .0270 | .0047 | .0003 |
| ΛDom | .1094 | .0516 | .0107 | .0007 |
| ΛRec | .1028 | .0164 | .0003 | .0000 |
| ΛAdd | .1041 | .0522 | .0112 | .0008 |
| ΛLarger | .0713 | .0271 | .0060 | .0003 |
| ΛUnc | .0732 | .0329 | .0059 | .0004 |
| n=200: | ||||
| ΛNew | .1158 | .0494 | .0075 | .0006 |
| ΛDom | .1064 | .0520 | .0095 | .0013 |
| ΛRec | .2008 | .0577 | .0039 | .0001 |
| ΛAdd | .1045 | .0531 | .0106 | .0011 |
| ΛLarger | .1057 | .0424 | .0064 | .0008 |
| ΛUnc | .1101 | .0484 | .0078 | .0006 |
| p=.3: | ||||
| n=100: | ||||
| ΛNew | .1068 | .0544 | .0118 | .0009 |
| ΛDom | .0869 | .0570 | .0120 | .0009 |
| ΛRec | .1111 | .0621 | .0145 | .0012 |
| ΛAdd | .1033 | .0536 | .0096 | .0005 |
| ΛLarger | .1134 | .0553 | .0138 | .0011 |
| ΛUnc | .1103 | .0580 | .0119 | .0013 |
| n=200: | ||||
| ΛNew | .0935 | .0445 | .0099 | .0017 |
| ΛDom | .1039 | .0539 | .0081 | .0009 |
| ΛRec | .0978 | .0493 | .0105 | .0020 |
| ΛAdd | .1035 | .0499 | .0082 | .0014 |
| ΛLarger | .0999 | .0499 | .0104 | .0014 |
| ΛUnc | .0971 | .0480 | .0113 | .0016 |
| p=.5: | ||||
| n=100: | ||||
| ΛNew | .0968 | .0487 | .0100 | .0006 |
| ΛDom | .1017 | .0498 | .0101 | .0011 |
| ΛRec | .1012 | .0509 | .0101 | .0006 |
| ΛAdd | .1014 | .0492 | .0106 | .0007 |
| ΛLarger | .1073 | .0546 | .0109 | .0010 |
| ΛUnc | .1039 | .0558 | .0115 | .0007 |
| n=200: | ||||
| ΛNew | .0977 | .0471 | .0084 | .0007 |
| ΛDom | .1008 | .0503 | .0088 | .0011 |
| ΛRec | .1023 | .0539 | .0102 | .0006 |
| ΛAdd | .1053 | .0525 | .0103 | .0009 |
| ΛLarger | .1054 | .0508 | .0088 | .0007 |
| ΛUnc | .1032 | .0488 | .0083 | .0006 |
Note.— Half of the sample is cases, and the other half is controls.