Table 6.
Haplotype Analysis of the rs3824068-rs2361688-rs1861972-rs1861973 Haplotype in AGRE I Data Seta
| Polymorphism, Diagnostic Criteria, and Haplotype | Frequency | P Valueb |
| rs3824068-rs2361688-rs1861972-rs1861973: | ||
| Narrow: | ||
| C-G-A-C | .357 | .996 |
| C-A-A-C | .008 | … |
| T-G-A-C | .357 | .054 |
| Broad: | ||
| C-G-A-C | .362 | .361 |
| C-A-A-C | .008 | … |
| T-G-A-C | .356 | .145 |
a
The 167 initial AGRE families (Gharani et al. 2004).
b
Haplotype-specific P values (1 df) generated by PDTPHASEsum (Dudbridge 2003). Only P values for haplotypes with a frequency >5% are presented, because the test statistic is not considered to retain its asymptotic validity for rare haplotypes. For each analysis, only haplotypes with the core rs1861972-rs1861973 A-C alleles are displayed.