TABLE 3.
Fatality rates for episodes of bloodstream infections caused by ESBL-producing versus ESBL-nonproducing E. coli or K. pneumoniae isolates by immune status and presence of shock at presentation
| Immune status | No. of fatal episodes/total no. of episodes (%)a for the indicated status at presentation:
|
||||
|---|---|---|---|---|---|
| ESBL group
|
Non-ESBL group
|
Total | |||
| Shock positive | Shock negative | Shock positive | Shock negative | ||
| Immunocompromised | 3/4 | 6/31 | 0/8 | 4/53 | 13/96 (13.5)b |
| Immunocompetent | 2/2 | 1/8 | 1/1 | 0/25 | 4/36 (11.1)b |
| Subtotal | 5/6 (83.3)c | 7/39 (17.9)d | 1/9 (11.1)c | 4/78 (5.1)d | |
Twelve of 45 patients (26.7%) in the ESBL group and 5 of 87 patients (5.7%) in the non-ESBL group died. The total number of deaths among patients in both groups was 17 (12.9%). The P value for the overall number of fatalities for the ESBL group versus that for the non-ESBL group, 0.001.
P value (Mann-Whiney U test) for immunocompetent group versus immunocompromised group, 1.0.
P value for mortality rate for the ESBL group versus that for the non-ESBL group among patients who presented with shock, 0.01.
P value for mortality rate for the ESBL group versus that for the non-ESBL group among patients who presented without shock, 0.04.