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. 2025 Dec 5;17:1641690. doi: 10.3389/fnagi.2025.1641690

Table 2.

The performance of predictive models on seven ML algorithms.

Models Training cohort Validation cohort
AUC Accuracy Recall Precision F1-score AUC Accuracy Recall Precision F1-score
XGBoost 1.00 0.99 1.00 0.97 0.99 0.69 0.66 0.46 0.47 0.47
GBM 0.76 0.62 0.78 0.41 0.54 0.71 0.62 0.72 0.44 0.55
RF 0.93 0.76 0.97 0.55 0.70 0.74 0.63 0.72 0.46 0.56
KNN 0.77 0.63 0.81 0.42 0.56 0.72 0.63 0.74 0.46 0.56
SVM 0.64 0.49 0.73 0.33 0.45 0.66 0.53 0.78 0.39 0.52
DT 0.70 0.72 0.50 0.52 0.51 0.65 0.66 0.42 0.48 0.45
LR 0.69 0.58 0.76 0.38 0.51 0.69 0.56 0.74 0.41 0.53

XGBoost, Extreme Gradient Boosting; GBM, Gradient Boosting Machine; RF, Random Forest; KNN, k-Nearest Neighbors; SVM, Support Vector Machines; DT, Decision Tree; LR, Logistic Regression.