TABLE 2.
Frequency of katG 315ACC allele among 204 INH-resistant M. tuberculosis strains revealed by PCR-RFLP analysis
| Phenotype and patient group | No. of strains with 315ACC allele/total no. of strains tested
|
% Strains with 315ACC allele | ||||
|---|---|---|---|---|---|---|
| 1996-1997 | 1998 | 1999 | 2000-2001 | Total | ||
| INHr | 29/30 | 28/30 | 84/92 | 50/52 | 191/204 | 93.6 |
| Previously diagnosed cases | 23/24 | 21/22 | 31/37 | 29/29 | 104/112 | 92.9 |
| INHr and RIFs | 0/0 | 7/7 | 2/3 | 2/2 | 11/12 | |
| INHr and RIFr | 23/24 | 14/15 | 29/34 | 27/27 | 93/100 | |
| New cases | 6/6 | 7/8 | 53/55 | 21/23 | 87/92 | 94.6 |
| INHr and RIFs | 1/1 | 2/2 | 15/16 | 6/8 | 24/27 | |
| INHr and RIFr | 5/5 | 5/6 | 38/39 | 15/15 | 63/65 | |
| Beijing genotype | 11/12 | 17/18 | 54/56 | 36/36 | 118/122 | 96.7 |
| Other genotypes | 18/18 | 11/12 | 30/36 | 14/16 | 73/82 | 89.0 |
| New cases, Beijing genotype | 3/3 | 4/4 | 34/34 | 14/14 | 55/55 | 100.0 |
| New cases, other genotypes | 3/3 | 3/4 | 19/21 | 7/9 | 32/37 | 86.5 |