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. 2025 Dec 5;12:1597788. doi: 10.3389/fnut.2025.1597788

Table 4.

Minimal Inhibitory Concentrations (MIC) and pathogen specificity of key Allium antimicrobial compounds.

Compound Target pathogen MIC value Specificity/notes
Allicin E. coli 0.125–20 μg/mL Effective against fermentative bacteria.
Allicin S. aureus 5–10 μg/mL Effective against Gram-positive cocci.
Allicin P. aeruginosa 20–80 μg/mL Less potent against non-fermentative bacteria.
Z-Ajoene Gram-positive bacteria 5–20 μg/mL Generally more active against Gram-positive strains.
Z-Ajoene Gram-negative bacteria 100–160 μg/mL Requires higher concentration for Gram-negative strains.
DADS (Diallyl Disulfide) C. albicans (Yeast) 20–40 μg/mL Also effective against yeasts.