Table 5.
Summarizing the mechanisms by which Allium species affect blood pressure, cholesterol, and cardiovascular health.
| Mechanism/aspect | Allium species | Key compounds | Effects on blood pressure and cholesterol |
|---|---|---|---|
| Blood pressure reduction | Garlic (Allium sativum) | Sulfur compounds (e.g., allicin) | Lowers systolic/diastolic BP by 5–7%; enhances nitric oxide release. |
| Lipid profile improvement | Garlic (Allium sativum) | OSCs | Reduces total cholesterol by ~10%, lowers LDL, improves HDL/LDL ratios. |
| Endothelial function | Onions (Allium cepa) | Flavonoids (e.g., flavonols, catechin) | Enhances endothelial function, reduces blood pressure. |
| Lipid metabolism regulation | Various Allium species | OSCs | Promotes LDL reduction and fecal lipid excretion, prevents hyperlipidemia. |
| Cardiovascular outcomes | Garlic and onions | OSCs, flavonoids | Reduces CVD risk factors (cholesterol, BP, obesity); lowers CVD incidence. |
All data in this table are supported by references cited in the main text.