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. 2025 Dec 5;12:1597788. doi: 10.3389/fnut.2025.1597788

Table 5.

Summarizing the mechanisms by which Allium species affect blood pressure, cholesterol, and cardiovascular health.

Mechanism/aspect Allium species Key compounds Effects on blood pressure and cholesterol
Blood pressure reduction Garlic (Allium sativum) Sulfur compounds (e.g., allicin) Lowers systolic/diastolic BP by 5–7%; enhances nitric oxide release.
Lipid profile improvement Garlic (Allium sativum) OSCs Reduces total cholesterol by ~10%, lowers LDL, improves HDL/LDL ratios.
Endothelial function Onions (Allium cepa) Flavonoids (e.g., flavonols, catechin) Enhances endothelial function, reduces blood pressure.
Lipid metabolism regulation Various Allium species OSCs Promotes LDL reduction and fecal lipid excretion, prevents hyperlipidemia.
Cardiovascular outcomes Garlic and onions OSCs, flavonoids Reduces CVD risk factors (cholesterol, BP, obesity); lowers CVD incidence.

All data in this table are supported by references cited in the main text.