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Sequence alignment of CRMPs and related proteins. Secondary structural elements were obtained from the X-ray structure. Gray circles denote disordered residues or residues not included in the construct (1–8, 526–572). Sequence homology is encoded by a gray → purple color gradient (40–100% identity). Functional classifications: 1, tetramer interface 1; 2, tetramer interface 2. Sequence numbering for mouse CRMP1 is provided in green above the secondary structure elements.
