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Summary of mCRMP1 mutants that had no effect on Sema3A-induced COS-7 cell contraction. (A) GRASP (Nicholls et al, 1991) representation of CRMP1 monomer highlighting the sites of 12 mutations with phenotypes identical to WT CRMP1 in the COS-7 contraction assay. (B) Quantitation of cell area (mean±s.e.m.) of COS-7 cells expressing PlexA1, NP1, and indicated mCRMP1 constructs.
