Table 1.
Frequency of progenya from Rb and Casp9 heterozygous intercrosses
| E13.5 | Rb+/±:Casp9+/± b | Rb−/−:Casp9+/± | Rb+/±:Casp9−/− | Rb−/−:Casp9−/− | Absorbed | Total |
|---|---|---|---|---|---|---|
| Observed | 81 | 18 | 27 | 5 | 10 | 131 |
| Expected | 73 (56.25%) | 25 (18.75%) | 25 (18.75%) | 8 (6.25%) | — | — |
| |
|
|
|
|
|
|
| E16.5 |
mgRb:Rb+/±:Casp9+/± |
mgRb:Rb−/−:Casp9+/± |
mgRb:Rb+/±:Casp9−/− |
mgRb:Rb−/−:Casp9−/− |
Absorbed |
Total |
| Observed | 102 | 20 | 19 | 8 | 6 | 149 |
| Expected |
84 (56.25%) |
28 (18.75%) |
28 (18.75%) |
9 (6.25%) |
— |
— |
| aGenotype was determined by PCR analysis of two independent biopsies from each embryo. | ||||||
| bEmbryos with at least one wild-type allele for Rb or Caspase9 were designated as +/±. | ||||||