Table 3. Diagnostic performance of HFC, CEA, and LDH for malignant effusion.

Biomarkers	AUC	95% CI	Cutoff value	Sensitivity (%)	Specificity (%)
HFC# (/μL)	0.703	0.671–0.736	20	70.2	60.3
HFC% (/100WBC)	0.727	0.695–0.758	2.1	78.3	56.8
CEA (ng/mL)	0.817	0.790–0.844	2.9	69.6	89.3
LDH (U/L)	0.553	0.516–0.590	146	80.4	35.2
HFC#+CEA	0.851	0.827–0.875		78.3	78.8
HFC%+CEA	0.855	0.832–0.878		74.6	79.3