TABLE 2.

Treatment of P. falciparum malaria with A-P

Study, yr (reference)	Country or group	Therapy (dose)a	No. (%b) of patients:
			Enrolled	Evaluated	Cured
Looareesuwan et al., 1996 (78)	Thailand	A-P (1,000/400 mg) for 3 days	24	24	24 (100)
Radloff et al., 1996 (100)	Gabon	A-P (1,000/400 mg) for 3 days	71	63	62 (87e)
		Amodiaquine at 600 g, 600 g, 300 mg	71	63	51 (72e)
de Alencar et al., 1997 (28)	Brazil	A-P (1,000 g/400 mg) for 3 days	NSc	77	76 (99)
		Quinine (600 mg) t.i.d. for 7 days + tetracycline (250 mg) q.i.d. for 7 days	NS	77	77 (100)
Sabchareon et al., 1998 (107)	Thailand	A-P (by wt) for 3 days	32	26	26 (100)
Looareesuwan et al., 1999 (79)	Thailand	A-P (1,000 g/400 mg) for 3 days	91	79	79 (100)
		Mefloquine at 750 mg once and then at 500 mg after 6 h	91	79	68 (86)
Mulenga et al., 1999 (88)	Zambia	A-P (1,000 g/400 mg) for 3 days	82	80	80 (100)
		Pyrimethamine (75 mg) + sulfadoxine (1,500 mg) once	81	80	79 (100)
Anabwani et al., 1999 (1)	Kenyad	A-P (by wt) for 3 days	84	81	76 (94)
		Halofantrine (8 mg/kg) every 6 h for three doses	84	83	75 (90)
Bustos et al., 1999 (15)	Philippines	A-P (by wt) for 3 days	55	54	54 (100)
		Chloroquine at 600 mg once and then at 300 mg once at 6, 24, and 48 h	23	23	7 (30)
		Chloroquine + pyrimethamine (75 mg) + sulfadoxine (1,500 mg) once	32	32	28 (88)
Bouchard et al., 2000 (12)	Nonimmune travelers	A-P (1,000 g/400 mg) for 3 days	25	21	21 (100)
		Halofantrine (500 mg) every 6 h for three doses	23	20	20 (100)

^at.i.d., three times a day; q.i.d., four times a day.

^bPercentage of evaluated patients

^cNS, not stated.

^dPediatric population.

^ePercentage of enrolled patients.