Time course of H. pylori titers in mice after single oral doses of metronidazole and methocel (control) (vehicle) compared to untreated, infected animals. The number of CFU/gram of gastric tissue is plotted for each animal within a dose group. Groups of animals were sacrificed on days 1, 4, 7, and 21 after the dosing day. BQL = approximately 103 CFU/g of tissue. QD, once daily.