TABLE 1.
Variability in time of one Aspergillus strain of each species to reach the three arbitrary growth curve criteriaa
| Strain | Criterion | 4-h incubation
|
2-h incubation
|
||
|---|---|---|---|---|---|
| Mean time (range)b | Upper 95% CI (CV) | Mean time (range)b | Upper 95% CI (CV) | ||
| A. fumigatus AZN VO2-33 | OD0 | 8.1 (7.5-9.6) | 9.8 (12.7) | 8.9 (8.2-10.6) | 10.7 (12.4) |
| OD20 | 11.7 (11.1-12.6) | 12.9 (6.6) | 11.7 (11.1-12.6) | 14.4 (4.7) | |
| OD50 | 24.4 (22.5-26.5) | 27.1 (6.7) | 24.3 (22.5-26.5) | 27.1 (6.7) | |
| A. terreus AZN 5914 | OD0 | 12.4 (12-12.7) | 13.1 (5.8) | 15 (14.2-15.7) | 16.4 (5.8) |
| OD20 | 21.7 (16.6-25.8) | 29.3 (22.0) | 24.2 (18.2-29.7) | 33.8 (25.1) | |
| OD50 | 28.9 (24.1-34.0) | 36.6 (16.6) | 30.2 (25.3-34.7) | 38.3 (16.8) | |
| A. ustus AZN 677 | OD0 | 12.7 (12-133.3) | 13.9 (6.1) | 8.5 (7.7-9.3) | 10 (10.7) |
| OD20 | 18.6 (14.7-24.9) | 25.9 (24.7) | 18 (15.6-24.3) | 24.7 (23.3) | |
| OD50 | 29.3 (20.9-35.3) | 40.7 (24.3) | 32.1 (23.8-38.2) | 43.4 (22.2) | |
| A. nidulans AZN 8950 | OD0 | 27.9 (27.2-28.7) | 29.3 (3.1) | 26.5 (25-28) | 29.3 (6.5) |
| OD20 | 25.4 (20-29.7) | 31.9 (16.1) | 26.8 (10.9-38.7) | 45.3 (43.2) | |
| OD50 | 34.7 (27.3-42.1) | 44.7 (18.2) | 38.2 (31.1-44.7) | 48.4 (16.7) | |
| A. flavus AZN 4094 | OD0 | 7.5 (6.2-9.9) | 12.7 (27.6) | 11 (10.3-11.4) | 12.5 (5.5) |
| OD20 | 14 (10.6-17.6) | 19.6 (25.3) | 18.8 (13.8-21.9) | 24.8 (20.1) | |
| OD50 | 25.3 (17.5-29) | 33.7 (21) | 25.2 (18.8-28.1) | 32.2 (17.3) | |
a
Strains were incubated for 2 or 4 hours to serve as controls for the drug-exposed isolates.
b
In hours.