TABLE 1.
MICs of various antibiotics for strains producing CTX-M-14 β-lactamases
| Antibiotica | MIC (μg/ml) against:
|
|||
|---|---|---|---|---|
| Clinical isolates (KTC984167) | Trans- conjugant | Cloned strains | JP-995 | |
| AMP | ≥32 | ≥32 | ≥32 | 2 |
| LOT | ≥32 | ≥32 | ≥32 | 4 |
| CFX | 8 | 2 | 8 | 4 |
| CTX | ≥64 | ≥64 | ≥64 | ≤0.25 |
| CTX plus CAL | ≤0.25 | ≤0.25 | ≤0.25 | ≤0.25 |
| CTR | ≥64 | ≥64 | ≥64 | ≤0.25 |
| CTR plus CAL | ≤0.5 | ≤0.5 | ≤0.5 | ≤0.5 |
| CPD | ≥64 | ≥64 | ≥64 | ≤0.5 |
| CPD plus CAL | ≤0.5 | ≤0.5 | 4 | ≤0.5 |
| CAZ | 2 | 1 | 16 | ≤0.25 |
| CAZ plus CAL | ≤0.25 | ≤0.25 | 0.5 | ≤0.25 |
| ATM | 8 | 4 | ≥64 | ≤0.25 |
| IMP | ≤0.25 | 0.5 | 0.5 | 0.5 |
| GEN | >8 | ≤0.5 | ≤0.5 | ≤0.5 |
| AMK | 4 | ≤2 | ≤2 | ≤2 |
| CIP | ≤0.06 | ≤0.06 | 0.25 | ≤0.06 |
a
Abbreviations: AMP, ampicillin; LOT, cephalothin; CFX, cefoxitin; CTX, cefotaxime; CAL, clavulanic acid; CTR, ceftriaxone; CPD, cefpodoxime; CAZ, ceftazidime; ATM, aztreonam; IMP, imipenem; GEN, gentamicin; AMK, amikacin; CIP, ciprofloxacin.