TABLE 1.
Treatment (concn [mg/kg]) | Mean log10 CFU/g of tissue (95% CIa)
|
||
---|---|---|---|
Liver | Spleen | Kidney | |
Control | 4.8 (4.5-5.0) | 5.7 (4.9-6.4) | 3.5 (2.9-4.1) |
AMB (1.5) | 4.2 (3.7-4.7) | 5.4 (5.1-5.7) | 3.7 (3.4-4.0) |
AMB (2.5) | 3.9 (3.2-4.7)b | 5.3 (4.6-6.0) | 3.7 (3.5-4.0) |
LAMB (3) | 2.5 (1.9-3.2)c | 4.5 (3.4-5.6) | 4.0 (3.1-4.8) |
LAMB (5) | 2.7 (2.3-3.1)c | 4.5 (3.5-5.4) | 3.7 (3.3-4.0) |
LAMB (10) | 2.3 (1.4-3.1)c | 3.2 (2.4-4.0)d | 3.4 (2.9-4.0) |
LAMB (20) | 2.4 (1.9-2.8)c | 3.3 (2.6-4.1)d | 3.4 (3.1-3.6) |
CI, confidence interval.
P < 0.05 versus control; P < 0.001 versus LAMB at 3, 5, 10, or 20 mg/kg.
P < 0.001 versus control or AMB at 1.5 or 2.5 mg/kg.
P < 0.01 versus control or AMB at 1.5 or 2.5 mg/kg.