TABLE 2.
Annualized All-Cause and AD-Related HCRU Among Switchers vs Nonswitchers Incurred During the Follow-Up Period
| Switchers (n = 466) | Nonswitchers (n = 7,597) | P value | |
|---|---|---|---|
| Follow-up duration in days, median (IQR) | 381 (373,388) | 379 (371,387) | — |
| All-cause HCRU | |||
| Hospitalizations | |||
| Total number of patients with ≥1 hospitalizations, n (%) | 25 (5.4) | 395 (5.2) | 0.83 |
| Annualized rate of hospitalizationsa, mean (SD) | 2.0 (2.8) | 1.3 (1.0) | 0.45 |
| ED visits | |||
| Total number of patients with ≥1 ED visit, n (%) | 148 (31.8) | 1,696 (22.3) | <0.01 |
| Annualized rate of ED visitsa, mean (SD) | 1.7 (1.4) | 1.8 (2.5) | 0.45 |
| Outpatient services | |||
| Total number of patients with ≥1 outpatient service, n (%) | 465 (99.8) | 7,538 (99.2) | 0.26 |
| Annualized rate of outpatient servicesa, mean (SD) | 26.9 (23.5) | 22.0 (22.5) | <0.01 |
| AD-related HCRU | |||
| Hospitalizations | |||
| Total number of patients with ≥1 hospitalizations, n (%) | 1 (0.2) | 1 (0) | 0.11 |
| Annualized rate of hospitalizationsa, mean (SD) | 1 (0) | 1 (0) | — |
| ED visits | |||
| Total number of patients with ≥1 hospitalizations, n (%) | 4 (0.9) | 4 (0.1) | <0.01 |
| Annualized rate of hospitalizationsa, mean (SD) | 1 (0) | 1 (0.2) | — |
| Outpatient services | |||
| Total number of patients with ≥1 outpatient services, n (%) | 449 (96.4) | 6,293 (82.8) | <0.01 |
| Annualized rate of outpatient servicesa, mean (SD) | 4.9 (5.0) | 3.1 (5.5) | <0.01 |
Unadjusted results tested using chi-square and Fisher exact tests.
a
Among patients with at least 1 event, rates were standardized to an annualized 360-day period.
AD = atopic dermatitis; ED = emergency department; HCRU = health care resource utilization; IQR = interquartile range.