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Extracellular and total azithromycin levels in MEF and serum in EOM due to NTHI
| MEF type | Day | Value obtained with azithromycin at:
|
|||||
|---|---|---|---|---|---|---|---|
| 30 (mg/kg/day)
|
120 (mg/kg/day)
|
||||||
| Level (μg/ml) in:
|
Ratio | Level (μg/ml) in:
|
Ratio | ||||
| MEF | Serum | MEF | Serum | ||||
| Extracellulara | 3 | 0.26 | 0.09 | 2.9 | 1.20 | 0.40 | 3.0 |
| 5 | 0.41 | 0.18 | 2.3 | 2.50 | 0.52 | 4.8 | |
| Totalb | 3 | 0.96 | 0.09 | 10.6 | 5.99 | 0.40 | 14.9 |
| 5 | 2.98 | 0.18 | 16.5 | 9.62 | 0.52 | 18.5 | |
MEF supernatant.
Freeze-thawed MEF.
