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In vitro activities of a series of dihydroethano- and ethaneanthracene derivatives against the CQ-resistant P. falciparum strain W2 and their effects on CQ CARs for CQ-susceptible and -resistant parasites
a
Me, methyl; Et, ethyl; Ph, phenyl.
b
IC50s for W2 are means of 4 to 12 independent experiments.
c
The values in parentheses are CQ CARs for CQ and the compound/CQ CAR of CQ alone.