TABLE 1.
MICs of 15 quinolones and other antibiotics, dyes, detergents, and disinfectants for S. aureus F77 and F145
| Agent(s)a | MICs (μg/ml) of S. aureus strains
|
|
|---|---|---|
| F77 | F145 | |
| Antibiotics | ||
| Nalidixic acid | 128 | 16 |
| Nalidixic acid + reserpine | 0.25 | 0.25 |
| Nalidixic acid + CCCP | 0.25 | 0.25 |
| Ciprofloxacin | 0.25 | 4 |
| Ciprofloxacin + reserpine | 0.25 | 1.6 |
| Ciprofloxacin + CCCP | 0.25 | 0.25 |
| Norfloxacin | 2 | 16 |
| Norfloxacin + reserpine | 0.2 | 0.4 |
| Tetracyclineb | 0.5 | 0.3 |
| Dyes | ||
| Acriflavine | 4 | 16 |
| Acridine orange | 8 | 4 |
| Ethidium bromide | 2 | 0.5 |
| Ethidium bromide + reserpine | 0.2 | 0.2 |
| Detergents | ||
| Dehydrocholic acid | 256 | 512 |
| Dehydrocholic acid + CCCP | 0.25 | 0.25 |
| Doxorubicin | 12.5 | 0.4 |
| CHAPS | 1024 | 1024 |
| SDS | 32 | 16 |
| TX-114 | 0.5 | 0.25 |
| NP-40 | 4 | <0.015 |
| Disinfectants | ||
| Cetrimide | 0.25 | 4 |
| Efflux pump inhibitors | ||
| TPP | 64 | 32 |
| CCCP | 64 | 512 |
| Reserpine | 128 | 512 |
a
CHAPS, 3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate; SDS, sodium dodecyl sulfate; TX-114, Triton X-114; NP-40, Nonidet P-40; TPP, tetraphenylophosphonium.
b
The MIC of tetracycline was determined three times using a decimal dilution method with increments of 0.1 μg/ml.