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. 2025 Dec 5;13(12):2992. doi: 10.3390/biomedicines13122992
ADAMTS5 A Disintegrin and Metalloproteinase with Thrombospondin Type 1 Motif 5
ANOVA analysis of variance
anti-CCP anti-cyclic citrullinated peptides
BMI body mass index
bv blood vessel
CTRLs controls
DAPI 4′,6-diamidino-2-phenylindole
DEGs differentially expressed genes
DRP1 Dynamin-Related Protein 1
EGFR Epidermal Growth Factor Receptor
ERK 1/2 Extracellular Signal-Regulated Kinase 1/2
FDR False discovery rate
GDE garlic-derived exosomes
GEO Gene Expression Omnibus
H&E Hematoxylin–eosin
HHS Harris Hip Score
HSS higher synovitis score group
ICAM-1 Intercellular Adhesion Molecule 1
ICC intraclass correlation coefficient
IHC Immunohistochemistry
IL-1β Interleukin-1 beta
INT intima
IQR interquartile range
JNK c-Jun N-terminal kinase
KEGG Kyoto Encyclopedia of Genes and Genomes
K-L Kellgren–Lawrence
MAPK mitogen-activated protein kinase
MMP-1 Matrix Metalloproteinase-1
NCBI National Center for Biotechnology Information
mRNA messenger RNA
OA Osteoarthritis
p38/SAPK p38 Mitogen-Activated Protein Kinase/stress-activated protein kinase
PBS phosphate-buffered saline
qRT-PCR quantitative real-time reverse transcription polymerase chain reaction
RA rheumatoid arthritis
RF rheumatoid factor
RNAseq RNA sequencing
ROI regions of interest
SD standard deviations
SUB subintima
TNF-α tumor necrosis factor alpha
VAS visual analog scale
WOMAC Western Ontario and McMaster Universities Arthritis Index