TABLE 2.

Interpretation of in vitro susceptibilities of 429 isolates of C. albicans and 118 isolates of C. tropicalis to fluconazole and itraconazole as determined by broth microdilution testing with four different methods of end point determination

Method of end point determinationa	No. of isolates in susceptibility category
	C. albicans (n = 429)						C. tropicalis (n = 118)
	Fluconazole			Itraconazole			Fluconazole			Itraconazole
	S	S-DD	R	S	S-DD	R	S	S-DD	R	S	S-DD	R
Visual, 24-h incubation	424	1	4	404	19	6	108	1	9	61	34	23
Visual, 48-h incubation	345	2	82	325	24	80	35	3	80	16	20	82
Spectrophotometric, 50% inhibition	422	2	5	408	17	4	108	3	7	77	34	7
Spectrophotometric, 80% inhibition	346	3	80	292	62	75	48	3	67	20	25	73

^aSpectrophotometric end points (with calculation of 50 and 80% growth inhibition) determined after a 48-h incubation.