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. 2025 Dec 9;30(24):4709. doi: 10.3390/molecules30244709
IN Integrase
DNA Deoxyribonucleic acid
ssRNA Single strand RNA
NTD N-terminal domain
CCD Central catalytic core domain
CTD C-terminal domain
LEDGF/p75 Lens-epithelium-derived growth factor
INSTIs Strand transfer inhibitors
ALLINIs Allosteric integrase inhibitors
IBD LEDGF/p75 Integrase Binding Pocket
SBS Sucrose binding site
RT ReverseTranscriptase
RNase H Ribonuclease H
RdRp RNA-dependent DNA polymerase
DEA Diethylamine
MM Molecular Mechanical
QM Quantum Mechanical
ACE Acetyl
DMSO N,N-Dimethylsulfoxide
XP Extra Precision
LEDGINs LEDGF/p75 inhibitors
TLC Thin-Layer Chromatography
NMA Methylamide
ALLINIs Allosteric HIV-1 integrase inhibitors
LYS Lysine
ALA Alanine
HIS Histidine
NDDO Neglect of diatomic differential overlap
GLN Glutamine
TYR Tyrosine
MM/GBSA Generalised born and surface area solvation