| IN | Integrase |
| DNA | Deoxyribonucleic acid |
| ssRNA | Single strand RNA |
| NTD | N-terminal domain |
| CCD | Central catalytic core domain |
| CTD | C-terminal domain |
| LEDGF/p75 | Lens-epithelium-derived growth factor |
| INSTIs | Strand transfer inhibitors |
| ALLINIs | Allosteric integrase inhibitors |
| IBD | LEDGF/p75 Integrase Binding Pocket |
| SBS | Sucrose binding site |
| RT | ReverseTranscriptase |
| RNase H | Ribonuclease H |
| RdRp | RNA-dependent DNA polymerase |
| DEA | Diethylamine |
| MM | Molecular Mechanical |
| QM | Quantum Mechanical |
| ACE | Acetyl |
| DMSO | N,N-Dimethylsulfoxide |
| XP | Extra Precision |
| LEDGINs | LEDGF/p75 inhibitors |
| TLC | Thin-Layer Chromatography |
| NMA | Methylamide |
| ALLINIs | Allosteric HIV-1 integrase inhibitors |
| LYS | Lysine |
| ALA | Alanine |
| HIS | Histidine |
| NDDO | Neglect of diatomic differential overlap |
| GLN | Glutamine |
| TYR | Tyrosine |
| MM/GBSA | Generalised born and surface area solvation |