TABLE 6.
Effect of 1263W94 and phosphorylated derivatives on the activity of HCMV DNA polymerase
| Inhibitor | HCMV DNA polymerase (% activity by limiting dNTP)
|
|||
|---|---|---|---|---|
| dATP | dCTP | dGTP | TTP | |
| 1263W94 | 91 | 96 | 90 | 91 |
| 1263W94-MP | 84 | 96 | 101 | 102 |
| 1263W94-TP | 86 | 89 | 100 | 108 |
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