Activities of tested antimicrobials (alone and in combination) versus MRSA 494 (A), MSSA 1199 (B), MRSE R444 (C), VREFc SF11848 (D), VREF 12311 (E), and GISA 992 (F). The key to symbols for each regimen is as follows: ampicillin (Amp, ▪); cefepime (Cfp, ✖); doxycycline (Dox, ⧫); linezolid (Lin, □); quinupristin-dalfopristin (Q-D, +); vancomycin (Van, ∗); ampicillin + quinupristin-dalfopristin (Amp + Q-D, ✖); cefepime + linezolid (Cfp + Lin, ◊); cefepime + quinupristin-dalfopristin (Cfp + Q-D, ○); cefepime + vancomycin (Cfp + Van, ); doxycycline + linezolid (Dox + Lin, ∗); linezolid + quinupristin-dalfopristin (Lin + Q-D, ★); linezolid + vancomycin (Lin + Van, ▪); quinupristin-dalfopristin + vancomycin (Q-D + Van, ⧫); growth control (GC, ⊡). The dotted line indicates the lower limit of detection (2.5 log10 CFU/ml) used for bacterial quantification.