Table 1.
Baseline characteristics by serum glycerol-3-phosphate tercile among participants from the PACE cohort
| G3P tercile | Overall (n = 99) | 1st tercile (n = 33) | 2nd tercile (n = 33) | 3rd tercile (n = 33) |
|---|---|---|---|---|
| Age (years) | 54 [44–63] | 57 [50–69] | 55 [44–63] | 50 [39–57] |
| Female | 38 (38%) | 11 (33%) | 18 (55%) | 9 (27%) |
| Race (Black) | 71 (71%) | 24 (73%) | 24 (73%) | 23 (70%) |
| Body Mass Index (kg/m2) | 25.8 [22.8–30.6] | 25.7 [22.7–30.4] | 25.6 [23.3–31.7] | 27.3 [22.9–29.7] |
| Coronary artery disease | 27 (27%) | 10 (30%) | 9 (27%) | 8 (24%) |
| Cardiovascular disease | 14 (14%) | 4 (12%) | 5 (15%) | 5 (15%) |
| Congestive heart failure | 29 (29%) | 8 (24%) | 11 (33%) | 10 (30%) |
| Total corrected calcium (mg/dL) | 9.0 [8.8–9.3] | 9.3 [8.8–9.5] | 8.9 [8.6–9.3] | 8.9 [8.7–9.4] |
| Phosphorus (mg/dL) | 5.1 [4.5–5.9] | 4.5 [4.1–5.0] | 5.0 [4.6–5.6] | 6.0 [5.1–6.5] |
| Parathyroid hormone (RU/mL) | 399.5 [269.6–581.3] | 321.5 [247.0–465.0] | 400.3 [257.1–605.8] | 528.0 [349.3–724.7] |
| Hemoglobin (g/dL) | 10.9 [9.5–11.8] | 10.8 [9.8–11.7] | 11.1 [10.2–11.8] | 10.7 [9.4–11.5] |
| Albumin (g/dL) | 3.8 [3.4–4.0] | 3.7 [3.4–4.0] | 3.8 [3.5–4.0] | 3.7 [3.3–4.0] |
| LDL (mg/dL) | 85.0 [60.2–104.2] | 69.5 [47.8–106.8] | 88.2 [68.3–100.8] | 78.6 [64.8–98.9] |
| C-terminal FGF23 | 776.9 [218.3–1329.7] | 324.0 [161.4–916.2] | 402.16 [206.0–810.8] | 1303.1 [884.0–1500.0] |
| C-reactive protein (µg/mL) | 4.5 [1.7–11.4] | 4.1 [1.5–13.4] | 4.7 [2.1–13.3] | 3.5 [1.8–9.1] |
| Ferritin (ng/mL) | 328.9 [185.4–573.0] | 374.0 [214.0–579.0] | 290.5 [167.7–591.2] | 302.7 [189.5–532.5] |
| Klotho (pg/mL) | 355.7 [268.3–489.7] | 355.7 [268.3–482.8] | 379.0 [304.7–537.4] | 338.3 [233.8–456.4] |
PACE = Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease
FGF-23 = Fibroblast factor-23
LDL= Low-density lipoprotein
Participant characteristics are compared between G3P categorical groups using Fisher’s exact test for categorical variables and using Kruskal-Wallis test for continuous variables. For continuous variables, values with normal distribution are as median [interquartile range].
Categorical variables are presented as absolute number (percentage).