FIG. 4.

Effects of candidate compounds on invasion of merozoites. P. falciparum cultures were grown in the presence of 6 μg of compound 1 per ml (left panel) or 6 μg of compound 4 per ml (right panel). After 24 h, samples of the cultures were removed and thin films were produced, fixed with methanol, and stained with 3% Giemsa stain in water for 30 min. The panels indicate representative fields of cultured RBCs-malarial parasites observed by microscopy. Note the extracellular locations of the parasites in the left panel. Magnifications, ×1,000.