FIG. 5.

Asynchronous parasite cultures (1 ml) were either untreated or treated with 500 μg of compound 1, 4, or 7 per ml for 24 h. The RBCs were then washed once in RPMI-A prior to addition of 10-μl aliquots to plates for the LDH assay (the values are the averages ± standard deviations of four values) and were used to produce blood films that were stained with Giemsa. The percentages of parasites present as ring or mature stages were then determined for each sample (n = 200 cells in each case).