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. 2002 Aug;46(8):2619–2626. doi: 10.1128/AAC.46.8.2619-2626.2002

FIG. 6.

FIG. 6.

Effects of compounds 1 (A), 4 (B), and 7 (C) on the time course of P. berghei parasitemia expressed as numbers of intracellular parasites/100 RBCs. Parasites were inoculated i.p., and treatment with compound 1, 4, or 7 was started 24 h later. Each dose of agent was given i.p. at 12-h intervals for a period of 9 days. •, no treatment; ▾, treatment with a dose of 0.6 mg; ▴, treatment with a dose of 4.8 mg; ▪, treatment with a dose of 38.4 mg. (A) Each point is the mean ± standard error of the mean for eight animals per time point. An ANOVA of between-group comparisons revealed significant differences (P < 0.001). (B) Each point is the mean ± standard error of the mean for eight animals per time point. An ANOVA of between-group comparisons revealed significant differences (P < 0.012). (C) Each point is the mean ± standard error of the mean for eight animals per time point. An ANOVA of between-group comparisons revealed no significant differences.