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Reactivity of human sera against C. neoformans CneF determined by ELISA. Sera were obtained from 12 HIV-positive cryptococcosis patients (black triangles). Sera obtained from laboratory workers (gray triangles) and other healthy volunteers (white triangles) were used as controls. All serum samples were used at a dilution of 1:200. One experiment, representative of three, each performed in duplicate, is shown. Bars represent means ± standard deviations. OD, optical density.
