Table 2.
Summary of Clinical, Imaging, and Histopathological Features of Diseases Presenting with Renal Mass Lesions.
| Clinicopathological features | Anastomosing hemangioma | IgG4-related kidney disease | Renal cell carcinoma (RCC) |
|---|---|---|---|
| Frequency | Rare | Rare | Common |
| Clinical manifestations | None or hematuria, flank pain | Renal dysfunction, mass lesions, proteinuria | Hematuria or bask pain, palpable mass |
| Histopathology | Benign vascular proliferation with anastomosing sinusoidal-like spaces | Dense lymphoplasmacytic infiltrate, storiform fibrosis, IgG4-positive plasma cells | Malignant epithelial cells forming glandular or solid structures |
| Immunohistochem-istry | CD31, CD34 positive | IgG4-positive plasma cells | PAX8, RCC marker positive |
| Radiological findings | Hypoattenuation, arterial enhancement on CT | Diverse lesions such as wedge-shaped areas | Hypervascular mass, often with necrosis on CT/MRI |
| Treatment | Surgical resection | Immunosuppressive therapy | Surgical resection, targeted therapy, immunotherapy |
RCC: Renal cell carcinoma