TABLE 2.
MICs of macrolides, lincosamides, and streptogramins
| S. aureus strain | Ribosomal mutation(s) (gene) | MIC (μg/ml)a of:
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| ERY | AZI | SPI | CLI | QUI | DAL | QUI-DAL | PRI | ||
| ATCC 29213 | None | 0.25 | 0.5 | 4 | 0.06 | 4 | 2 | 1 | 0.12 |
| UCN13 | A2058G (rrl) | >128 | >128 | >128 | 16 | 64 | 2 | 1 | 0.5 |
| UCN14 | A2058T (rrl) | >128 | >128 | 128 | 1 | 32 | 0.5 | 0.25 | 0.12 |
| UCN15 | A2058G (rrl), deletion (rplV) | >128 | >128 | 128 | 2 | 32 | 4 | 4 | 1 |
| UCN16 | A2058G (rrl) | >128 | >128 | 8 | 0.5 | 8 | 0.25 | 0.25 | 0.12 |
| UCN17 | A2058G (rrl) | >128 | >128 | 128 | 16 | 16 | 4 | 0.5 | 0.25 |
| UCN18 | A2059G (rrl) | >128 | >128 | 128 | 1 | 2 | 2 | 0.25 | 0.12 |
a
Abbreviations: AZI, azithromycin; CLI, clindamycin; DAL, dalfopristin; ERY, erythromycin; PRI, pristinamycin; QUI, quinupristin; QUI-DAL, quinupristin-dalfopristin; SPI, spiramycin.