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. 2002 Sep;46(9):2727–2734. doi: 10.1128/AAC.46.9.2727-2734.2002

FIG. 2.

FIG. 2.

Secondary structures of hairpin 35 in domain II (top) and in domain V (bottom) of 23S rRNA in E. coli. Nucleotides which are protected by erythromycin are circled (43). Arrows indicate mutations conferring macrolide resistance on S. pneumoniae. The corresponding phenotype is indicated (K, ketolides; L, lincosamides; M, macrolides; M16, 16-membered macrolides; SB, streptogramin B; S, streptogramin A and streptogramin B). Small capital letters denote low-level resistance.

HHS Vulnerability Disclosure