Table 3.

Average Z-scores for prob_score and ProfNet_S for the scores for different types of conserved residue pairs. ProfNet_S was trained on superfamily related profile vector pairs and using the S-score as a classifier. The pairs are grouped into pairs with identical residues, positive, zero and negative BLOSUM scores. Finally, the Z-scores for a pair containing one conserved and one non-conserved residue and two non-conserved residues are shown. The highest scores are shown in bold.

	prob_score	ProfNet_S
identical res	3.09	2.50
pos BLOSUM	1.46	1.99
zero BLOSUM	0.44	1.10
neg BLOSUM	-0.91	0.22
cons-non cons	0.21	0.15
non cons-non cons	1.06	0.53