Table 3.
SNP Name | Caucasian | African American | ||||||||||
Major/Major | Major/Minor | Minor/Minor | Major/Major | Major/Minor | Minor/Minor | |||||||
DM | Cnt | DM | CNT | DM | CNT | DM | CNT | DM | CNT | DM | CNT | |
SNP 1 | 120 | 124 | 54 | 59 | 6 | 7 | 249 | 117 | 84 | 60 | 7 | 9 |
SNP 2 | 54 | 61 | 97 | 95 | 38 | 34 | 197 | 124 | 53 | 35 | 2 | 3 |
SNP 3 | 97 | 73 | 15 | 108 | 71 | 12 | --- | --- | --- | --- | --- | --- |
SNP 4 | 84 | 82 | 43 | 76 | 89 | 26 | 169 | 147 | 25 | 79 | 75 | 31 |
SNP 5 | --- | --- | --- | --- | --- | --- | 210 | 143 | 34 | 14 | 1 | 0 |
SNP 6 | 124 | 125 | 56 | 58 | 7 | 9 | 200 | 119 | 53 | 43 | 2 | 3 |
SNP 8 | 123 | 123 | 56 | 58 | 9 | 7 | 198 | 115 | 50 | 41 | 2 | 3 |
SNP 11 | 125 | 8 | 51 | 125 | 53 | 6 | 253 | 114 | 76 | 57 | 7 | 11 |
ProIns | --- | --- | --- | --- | --- | --- | 265 | 57 | 1 | 155 | 21 | 0 |
Numbers of individuals with each genotype are shown for the SNPs in Table 1. Significance by allelic association is shown in Table 1 with confidence intervals for allele frequencies. Note that allelic association was the primary test performed. Data not shown (--) was not typed in the full case control set because of low frequency. Counts differ slightly due to genotypes that were not called, and because additional African American samples were typed for SNPs 1, 4, 11, and ProIns (proline insertion) based on initial data showing an association.