Table 2.
Allele and genotype frequency at marker rs 175174 in schizophrenic psychoses
| Allele (%) | Genotypes (%) | ||||||
| Samples | A | G | p-value | AA | AG | GG | p-value |
| total | |||||||
| SCZ (N = 433) | 527 (60.9) | 339 (39.1) | 0.48 | 154 (35.6) | 219 (50.6) | 60 (13.9) | 0.43 |
| CON (N = 186) | 235 (63.2) | 137 (36.8) | 71 (38.2) | 93 (50.0) | 22 (11.8) | ||
| females | |||||||
| SCZ (N = 112) | 125 (55.8) | 99 (44.2) | 0.25 | 30 (26.8) | 65 (58.0) | 17 (15.2) | 0.20 |
| CON (N = 81) | 100 (61.7) | 62 (38.3) | 27 (33.3) | 46 (56.8) | 8 (9.9) | ||
| males | |||||||
| SCZ (N = 321) | 402 (62.6) | 240 (37.4) | 0.68 | 124 (38.6) | 154 (48.0) | 43 (13.4) | 0.66 |
| CON (N = 105) | 135 (64.3) | 75 (35.7) | 44 (41.9) | 47 (44.8) | 14 (13.3) | ||
| family history | |||||||
| sporadic SCZ (N = 369) | 441 (59.8) | 297 (40.2) | 0.12 | 124 (33.6) | 193 (52.3) | 52 (14.1) | 0.10 |
| familial SCZ (N = 64) | 86 (67.2) | 42 (32.8) | 30 (46.9) | 26 (40.6) | 8 (12.5) | ||
SCZ: probands with schizophrenia; CON: controls; p-values for alleles (Fisher's exact test) and genotypes (Armitage's trend test).