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This figure was independently created by synthesizing KDIGO’s conceptual framework [3] with findings from multiple recent mechanistic publications.
SGLT 2 = Sodium-glucose cotransporter 2, RAAS = Renin-angiotensin-aldosterone system, BAFF = B-cell activating factor, APRIL = A proliferation-inducing ligand, MMF = Mycophenolate mofetil, IgG-Gd-IgA1 = Immunoglobulin G-galactose-deficient immunoglobulin A1
