TABLE 1.

Clinical pharmacokinetic study summary

Patient no.	Treatment drug regimen	Tacrolimus dose (mg)	Tacrolimus trough blood concn (ng/ml)
			Pretherapy	Day 3	Day 5
1	Voriconazole 200 mg orally twice a day (days 0 to 5)	2	2.3	12.5	23.4
2	Placebo (days 0 to 6)	4	4.3	3.4	6.2