Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Serum and MEF pharmacodynamic data of amoxicillin in relation to the eradication of S. pneumoniae
| Amoxicillin treatment group dose (mg/kg) | Serum
|
MEF antibiotic concn/ MIC | % Eradication | ||
|---|---|---|---|---|---|
| C15min/MIC | T > MIC (min) (% dose interval) | AUC/MICb | |||
| 2.5 | 4.7 | 69 (14.3) | 4.3 | 1.4 | 95 |
| 5.0 | 12.2 | 93 (19.4) | 10.2 | 2.4 | 100 |
Antibiotic concentration in MEF 90 min after drug administration.
AUC, area under the curve.
