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. 2025 Dec 16;16:1674276. doi: 10.3389/fneur.2025.1674276

Table 2.

Baseline data of sICH patients in the training cohort.

Variables Poor outcome (n = 95) Favorable outcome (n = 59) P
Age (y) 61.35 ± 13.64 54.83 ± 14.49 0.006
Male/Female 68/27 47/12 0.352
Hypertension 63 (66.3%) 30 (50.8%) 0.082
Coronary heart disease 8 (8.4%) 2 (3.4%) 0.371
Diabetes 12 (12.6%) 4 (6.8%) 0.376
Temperature (°C) 36.5 (36.5, 36.7) 36.5 (36.5, 36.6) 0.070
Systolic blood pressure (mmHg) 174.33 ± 32.64 170.34 ± 27.91 0.438
Diastolic blood pressure (mmHg) 97.97 ± 19.15 100.34 ± 19.66 0.461
GCS score 8.00 (6.00, 11.00) 12.00 (9.00, 13.5) <0.001
Pupil abnormality 53 (55.8%) 17 (28.8%) 0.002
Blood glucose (mmol/L) 8.45 (7.00, 9.86) 7.67 (6.35, 9.07) 0.054
D-Dimer (mg/L) 361.30 (160.55, 1163.25) 292.30 (142.70, 579.50) 0.173
C-reactive protein (mg/L) 3.32 (1.44, 6.33) 3.30 (1.05, 7.14) 0.676
Neutrophil-lymphocyte ratio 10.10 (6.84, 16.90) 10.52 (5.94, 16.71) 0.595
Hemoglobin (g/L) 129.18 ± 22.27 140.49 ± 17.12 0.001
Platelet count (109/L) 194.25 ± 70.73 202.98 ± 55.40 0.421
Activated partial thromboplastin time (s) 33.30 (30.90, 36.00) 33.20 (30.70, 35.10) 0.433
International normalized ratio 0.99 (0.93, 1.05) 0.97 (0.93, 1.00) 0.220
Fibrinogen (mg/dL) 3.02 ± 0.87 2.91 ± 0.55 0.388
Hematoma volume 57.50 (43.30, 87.40) 44.70 (27.90, 57.00) <0.001
Hematoma location 0.004
 Lobar hematoma 15 (15.8%) 22 (37.3%)
 Deep hematoma 80 (84.2%) 37 (62.7%)
Hydrocephalus 33 (34.7%) 6 (10.2%) 0.001
Subarachnoid hemorrhage 16 (16.8%) 10 (16.9%) 1.000
Intraventricular hemorrhage 63 (66.3%) 29 (49.2%) 0.052
Brain herniation 33 (34.7%) 3 (5.1%) <0.001
Midline shift 51 (53.7%) 19 (32.2%) 0.015
Time interval from NCCT to surgery (h) 4.00 (2.00, 6.00) 5.00 (3.00, 9.00) 0.029
Surgical approach 0.319
 Minimally invasive surgery 72 (75.8%) 49 (83.1%)
 Craniotomy 23 (24.2%) 10 (16.9%)
Surgical duration (h) 3.36 ± 1.87 2.66 ± 1.53 0.017
Intraoperative bleeding (mL) 222.00 (103.50, 422.00) 122.00 (22.00, 322.00) 0.009
Blood transfusion (mL) 67.96 ± 172.91 38.98 ± 135.21 0.275
mRS score 4.00 (4.00, 5.00) 3.00 (2.00, 3.00) <0.001
Early rehabilitation 21 (22.1%) 11 (18.6%) 0.756
Flatness 0.52 ± 0.92 −0.24 ± 0.93 <0.001
Least axis length 0.24 ± 0.83 −0.26 ± 0.92 0.001
VolumeCC 0.07 ± 0.05 0.04 ± 0.02 0.001
Radscore 48.33 ± 64.63 −23.55 ± 75.33 <0.001

Data are expressed as mean ± standard deviation, median (1st quartile, 3rd quartile), or frequency (percentage).