Table 2.

The relationship between DCUN1D5 expression and clinicopathological characteristics

Parameters	Total (n = 56)	DCUN1D5					2		P
		Negative (-)	Weakly positive (+)	Moderately positive (++)	Strongly positive (+++)
Gender
Male	46	6 (13.0%)	16 (34.8%)	18 (39.1%)	6 (13.0%)		3.411		0.332
Female	10	2 (20.0%)	1 (10.0%)	4 (40.0%)	3 (30.0%)
Age (years)
≥ 65	37	6 (16.2%)	11 (29.7%)	13 (35.1%)	7 (18.9%)		3.712		0.716
< 65	18	2 (11.1%)	5 (27.8%)	9 (50.0%)	2 (11.1%)
Unknown	1	0 (0%)	1 (100%)	0 (0%)	0 (0%)
Histologic grade
Poorly	46	3 (6.5%)	14 (30.4%)	20 (43.5%)	9 (19.6%)		23.571		0.000*
Well	7	5 (71.4%)	1 (14.3%)	1 (14.3%)	0 (0%)
Unknown	3	0 (0%)	2 (66.7%)	1 (33.3%)	0 (0%)
Depth of invasion
MIBC	36	2 (5.6%)	8 (22.2%)	18 (50.0%)	8 (22.2%)		14.922		0.021*
NMIBC	16	4 (25.0%)	7 (43.8%)	4 (25.0%)	1 (6.3%)
Unknown	4	2 (50.0%)	2 (50.0%)	0 (0%)	0 (0%)
Lymph node
YES	7	2 (28.6%)	2 (28.6%)	2 (28.6%)	1 (14.3%)		9.079		0.169
NO	39	3 (7.7%)	10 (25.6%)	19 (48.7%)	7 (17.9%)
Unknown	10	3 (30.0%)	5 (50.0%)	1 (10.0%)	1 (10.0%)
Tumor number
Multiple	7	3 (42.9%)	2 (28.6%)	2 (28.6%)	0 (0%)		9.704		0.138
Solitary	43	3 (7.0%)	13 (30.2%)	19 (44.2%)	8 (18.6%)
Unknown	6	2 (33.3%)	2 (33.3%)	1 (16.7%)	1 (16.7%)
T status
Tis	4	0 (0%)	1 (25.0%)	3 (75.0%)	0 (0%)		28.490		0.019*
T1	11	3 (27.3%)	7 (63.6%)	0 (0%)	1 (9.1%)
T2	14	2 (14.3%)	3 (21.4%)	6 (42.9%)	3 (21.4%)
T3	21	0 (0%)	5 (23.8%)	11 (52.4%)	5 (23.8%)
T4	1	0 (0%)	0 (0%)	1 (100%)	0 (0%)
Unknown	5	3 (60.0%)	1 (20.0%)	1 (20.0%)	0 (0%)
Tumor size
3 cm	7	2 (28.6%)	22 (28.6%)	12 (14.3%)	2 (28.6%)		10.652		0.300
5 cm	21	32 (14.3%)	4 (19.0%)	12 (57.1%)	2 (9.5%)
5 cm	22	1 (4.5%)	9 (40.9%)	8 (36.4%)	4 (18.2%)
Unknown	6	2 (33.3%)	2 (33.3%)	1 (16.7%)	1 (16.7%)
Stage
III	21	2 (9.5%)	7 (33.3%)	8 (38.1%)	4 (19.0%)		12.268		0.056
III	26	2 (7.7%)	6 (23.1%)	13 (50.0%)	5 (19.2%)
Unknown	9	4 (44.4%)	4 (44.4%)	1 (11.1%)	0 (0%)
Tumor subtype
Papillary	18	6 (33.3%)	5 (27.8%)	5 (27.8%)	2 (11.1%)		8.095		0.044*
Non papillary	38	2 (5.3%)	12 (31.6%)	17 (44.7%)	7 (18.4%)

*P0.05