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Intranasal prophylactic efficacy of RFI-641 in cotton rats
| Study no. | Strain | Mean control titer ± SD (log10 PFU/lung) | Dose (mg/kg) | Log10 reduction |
|---|---|---|---|---|
| 1 | A2 | 4.3 ± 0.23 | 0.2 | 0.6 |
| 2 | A2 | 3.9 ± 0.24 | 1.0 | 3.2a |
| 3.3 | 3.2a | |||
| 10 | 3.2a | |||
| 3 | Long | 4.6 ± 0.45 | 10 | 2.6a |
Significance at a P value of <0.05 by Student's t test based on 5 mice per group.
