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. 2025 Dec 29;15:44797. doi: 10.1038/s41598-025-28706-y

Table 3.

Physical and mental health of participants.

Variables Total (n = 16,276) Male (n = 7,718) Female (n = 8,558) P value
Have chronic diseases
0 5,714 (35.1) 2,894 (37.5) 2,820 (33.0) < 0.001
1 5,806 (35.7) 2,818 (36.5) 2,988 (34.9)
≥ 2 4,756 (29.2) 2,006 (26.0) 2,750 (32.1)
Hypertension 0.039
Yes 7,538 (46.3) 3,509 (45.5) 4,029 (47.1)
No 8,738 (53.7) 4,209 (54.5) 4,529 (52.9)
Hyperlipidemia < 0.001
Yes 1,185 (7.3) 442 (5.7) 743 (8.7)
No 15,091 (92.7) 7,276 (94.3) 7,815 (91.3)
Coronary artery disease 0.156
Yes 644 (4.0) 323 (4.2) 321 (3.8)
No 1,5632 (96.0) 7,395 (95.8) 8,237 (96.2)
Emphysema < 0.001
Yes 73 (0.4) 56 (0.7) 17 (0.2)
No 16,203 (99.6) 7,662 (99.3) 8,541 (99.8)
Tuberculosis 0.101
Yes 95 (0.6) 53 (0.7) 42 (0.5)
No 16,181 (99.4) 7,665 (99.3) 8,516 (99.5)
Asthma 0.155
Yes 101 (0.6) 55 (0.7) 46 (0.5)
No 16,175 (99.4) 7,663 (99.3) 8,512 (99.5)
Chronic bronchitis < 0.001
Yes 438 (2.7) 265 (3.4) 173 (2.0)
No 15,838 (97.3) 7,453 (96.6) 8,385 (98.0)
Gallstones < 0.001
Yes 859 (5.3) 281 (3.6) 578 (6.8)
No 15,417 (94.7) 7,437 (96.4) 7,980 (93.2)
Nephritis 0.430
Yes 61 (0.4) 32 (0.4) 29 (0.3)
No 16,215 (99.6) 7,686 (99.6) 8,529 (99.7)
Tumor 0.668
Yes 371 (2.3) 180 (2.3) 191 (2.2)
No 15,905 (97.7) 7,538 (97.7) 8,367 (97.8)
Parkinson’s disease 0.220
Yes 48 (0.3) 27 (0.3) 21 (0.2)
No 16,228 (99.7) 7,691 (99.7) 8,537 (99.8)
Cataract < 0.001
Yes 1,328 (8.2) 488 (6.3) 840 (9.8)
No 14,948 (91.8) 7,230 (93.7) 7,718 (90.2)
Glaucoma 0.209
Yes 54 (0.3) 21 (0.3) 33 (0.4)
No 16,222 (99.7) 7,697 (99.7) 8,525 (99.6)
Gastric disease < 0.001
Undiagnoseda 1,127 (6.9) 461 (6.0) 666 (7.8)
Diagnosedb 1,149 (7.1) 492 (6.4) 657 (7.7)
No 14,000 (86.0) 6,765 (87.7) 7,235 (84.5)
Diabetes < 0.001
Yes 1,804 (11.1) 728 (9.4) 1,076 (12.6)
No 14,472 (88.9) 6,990 (90.6) 7,482 (87.4)
Hepatitis 0.017
Yes 141 (0.9) 81 (1.0) 60 (0.7)
No 16,135 (99.1) 7,637 (99.0) 8,498 (99.3)
Arthritis 0.004
Yes 794 (4.9) 337 (4.4) 457 (5.3)
No 15,482 (95.1) 7,381 (95.6) 8,101 (94.7)
Thyroid disease < 0.001
Yes 402 (2.5) 98 (1.3) 304 (3.6)
No 15,874 (97.5) 7,620 (98.7) 8,254 (96.4)
Depressive symptom 0.033
None 14,953 (91.9) 7,137 (92.5) 7,816 (91.3)
Mild 938 (5.8) 417 (5.4) 521 (6.1)
Moderate 245 (1.5) 100 (1.3) 145 (1.7)
Moderate-severe 53 (0.3) 20 (0.3) 33 (0.4)
Severe 87 (0.5) 44 (0.6) 43 (0.5)
ADL (Barthel index) 0.045
Independence (100) 15,806 (97.1) 7,525 (97.5) 8,281 (96.8)
Slight dependence (91–99) 212 (1.3) 88 (1.1) 124 (1.4)

Moderate

Dependence (61–90)

200 (1.2) 80 (1.0) 120 (1.4)
Indicating severe dependence (0–60) 58 (0.4) 25 (0.3) 33 (0.4)
Cognitive impairment < 0.001
Yes 3,222 (19.8) 1,383 (17.9) 1,839 (21.5)
No 13,054 (80.2) 6,335 (82.1) 6,719 (78.5)
Multimorbidityc < 0.001
Yes 6,335 (38.9) 2,720 (35.2) 3,615 (42.2)
No 9,941 (61.1) 4,998 (64.8) 4,943 (57.8)

a “Undiagnosed” indicates that the participant reported symptoms suggestive of gastrointestinal issues in the absence of a formal diagnosis through clinical evaluation at a hospital.

b “Diagnosed” indicates that the gastric disease of the participants had been diagnosed at a hospital.

cMultimorbidity, defined as the coexistence of two or more chronic conditions encompassing both physical and mental health disorders.