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Cytotoxic effect of APC1 on trophozoites of A. castellanii (strain 1BU). (a) Trophozoite monolayer before treatment, 30 min after treatment, and 1 h after treatment with 80 μM APC1, from left to right, respectively. (b) Representative single trophozoite before treatment, after 15 min (note the blebbing of the cell), after 30 min (disappearance of cytoplasmic structures), and after 1 h (lysis), from left to right, respectively.
