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Represent The clinical trial of CRISPR-CAS9. (https://clinicaltrials.gov). The table represent different clinical trials of phase 1 in various cancer using CRISPR-CAS9 system
| Clinical Trial | CANCER TYPE | Related CRISPR Method |
|---|---|---|
| Phase 1 | Refractory cancers | Delete two genes that encode TCR and a gene encoding PD-1 |
| Advanced NSCLC | Edite PD-1 on T cells | |
| Mesothelin-positive solid tumors | PD-L1 possible target for knockout | |
| Refractory solid cancers | Knockout two (TCR) gene |
