Table 3.
Heatmap representing qPCR analysis of genes of interest
| Genes | Ctrl IgG | Ctrl FGF23Ab | SCD IgG | SCD FGF23Ab | |
|---|---|---|---|---|---|
| Fgf23 | 0.86 | 0.91 | 0.95 | 0.93 | |
| Fgfr1c | 0.94 | 0.81 | 1.07 | 0.79 | c |
| Fgfr2 | 1.18 | 0.80 | 2.59 | 2.23 | a |
| Fgfr3c | 1.23 | 0.49 | 2.48 | 1.77 | a b c |
| aKlotho | 0.95 | 0.65 | 0.79 | 0.87 | |
| Mgp | 0.91 | 1.14 | 0.78 | 0.67 | |
| Mepe | 0.96 | 0.60 | 2.83 | 1.58 | a b c |
| Phex | 1.07 | 0.34 | 2.72 | 2.58 | a b |
| Dmp1 | 0.99 | 0.50 | 0.81 | 0.69 | b |
| Enpp1 | 1.01 | 1.16 | 2.18 | 1.06 | a c |
| Ank | 1.03 | 1.22 | 0.93 | 0.96 | |
| Pit2 | 1.00 | 0.99 | 1.25 | 0.82 | |
| Tnap | 1.06 | 0.57 | 1.78 | 1.62 | a b |
Data are presented as mean (n = 6 wells per group). Significance annotations:
Ctrl-IgG vs. SCD-IgG, p < 0.05
Ctrl-IgG vs. Ctrl-FGF23Ab, p < 0.05
SCD-IgG vs. SCD-FGF23Ab, p < 0.05.
p-values were determined using two-way ANOVA followed by Tukey’s post hoc test.