Table 1.
Hemodynamic parameters in rats with sham operation (control) or cirrhosis induced by common BDL
| Hemodynamic parameters | Control (n = 6) | BDL (n = 8) |
|---|---|---|
| BW (g) | 460 ± 14 | 403 ± 11b |
| PP (mmHg) | 8.3 ± 0.4 | 16.8 ± 0.7c |
| Systemic circulation | ||
| MAP (mmHg) | 148 ± 5 | 131 ± 6 |
| HR (beats/min) | 380 ± 15 | 379 ± 6 |
| CI (mL/min/100 g) | 35.9 ± 1.5 | 41.4 ± 2.9 |
| SVR (mmHg/mL/min/100 g) | 4.2 ± 0.2 | 3.3 ± 0.3a |
| Splanchnic system | ||
| SMA flow (mL/min/100 g) | 4.3 ± 0.2 | 5.7 ± 0.3b |
| Portal system | ||
| Hepatic inflow (portal part) (mL/min/100 g) | 5.6 ± 0.3 | 11.3 ± 0.4c |
| Collateral system | ||
| SRS flow (mL/min/100 g) | 0.04 ± 0.01 | 1.58 ± 0.28c |
BDL = bile duct ligation; BW = body weight; CI = cardiac index; HR = heart rate; MAP = mean arterial pressure; PP = portal pressure; SMA = superior mesenteric artery; SRS = splenorenal shunt; SVR = systemic vascular resistance.
a
p < 0.05.
b
p < 0.01.
c
p < 0.001.