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. 2005 Aug 16;77(4):545–555. doi: 10.1086/491602

Figure 6.

Figure 6

LOD scores along chromosome 18 from the LODPAL and OSA analyses of the NIMH sample (n=150 families) under the broad- and narrow-phenotype models are presented. For the LODPAL analyses, results from the one-covariate model with AAO as a continuous variable are shown. For the OSA analyses, results from the high-to-low slicing of the data set are shown. Baseline models without AAO, which generally yielded LOD scores <0.05, are not shown, for the sake of clarity. The results from both sets of analyses converged at chromosome 18p11.2 and showed increased evidence of linkage among affected subjects with later-onset BP (AAO>21 years).