Table 5.

Estimated Frequencies of Submicroscopic Aberrations for Each Clinical Score, in the Study Cohorts and an Unselected Cohortof Patients with MR^[Note]

	Study Cohorts							Unselected Cohort (n=120)
	Array CGH Tested(n=100)			MLPA Tested(n=297)
ClinicalScore	No. ofPatients	No. ofAberrations	Prevalence	No. ofPatients	No. ofAberrations	Prevalence	CombinedPrevalence	No. ofPatients	EstimatedFrequency ofAberrations
0	0	0	.00	1	0	.00	.00	20	.0
1	5	0	.00	36	1	.03	.03	25	.7
2	16	0	.00	58	1	.02	.02	33	.6
3	32	5	.16	86	5	.06	.21	17	3.5
4	21	1	.05	62	1	.02	.06	14	.9
5	14	1	.07	32	4	.13	.19	4	.8
6	7	1	.14	15	1	.07	.20	5	1.0
7	5	2	.40	6	0	.00	.40	1	.4
8	0	0	.00	1	1	1.00	1.00	1	1.0
9	0	0	.00	0	0	.00	.00	0	.0
10	0	0	.00	0	0	.00	.00	0	.0
Total	100	10	.10	297	14	.05	.14	120	8.8

Note.— The estimations are based on the combined prevalences of the submicroscopic anomalies in the study cohorts.