Table 2.
Two-Point LOD Scores for 7q36 Markers in Family 1270
| LOD at θ= |
||||||||
| Markera | Distanceb(cM) | .00 | .01 | .05 | .10 | .20 | .30 | .40 |
| D7S661 | .0 | −1.31 | −.93 | −.40 | −.15 | .01 | .02 | .01 |
| D7S668 | 4.4 | −.68 | .34 | .97 | 1.15 | 1.09 | .78 | .32 |
| D7S505 | 6.1 | .30 | 1.28 | 1.76 | 1.80 | 1.52 | 1.03 | .43 |
| D7S636 | 7.2 | 2.69 | 2.65 | 2.46 | 2.22 | 1.68 | 1.08 | .43 |
| pRR8c | … | −1.08 | −.09 | .53 | .73 | .70 | .45 | .15 |
| D7S642 | 7.2 | 1.26 | 1.29 | 1.32 | 1.26 | 1.01 | .64 | .24 |
| D7S2439 | 8.6 | 2.88 | 2.83 | 2.62 | 2.34 | 1.74 | 1.09 | .42 |
| D7S483 | 10.1 | 3.32 | 3.27 | 3.04 | 2.74 | 2.08 | 1.34 | .55 |
| D7S798 | 13.9 | 3.39 | 3.33 | 3.11 | 2.81 | 2.14 | 1.38 | .57 |
| D7S1807d | … | 3.41 | 3.36 | 3.14 | 2.84 | 2.16 | 1.40 | .58 |
| D7S2546 | 17.9 | 2.51 | 2.47 | 2.26 | 1.99 | 1.41 | .82 | .28 |
| D7S1823 | 18.6 | 2.72 | 2.69 | 2.52 | 2.29 | 1.74 | 1.12 | .44 |
| pRR10c | … | 1.95 | 1.90 | 1.73 | 1.52 | 1.07 | .61 | .20 |
| D7S2465 | 25.1 | 1.70 | 1.67 | 1.56 | 1.41 | 1.06 | .65 | .23 |
| pRR15c | … | 3.11 | 3.06 | 2.85 | 2.57 | 1.95 | 1.26 | .52 |
| D7S559 | 26.9 | 1.41 | 1.61 | 1.84 | 1.82 | 1.49 | .98 | .38 |
| D7S2423 | 26.9 | −1.04 | −.82 | −.45 | −.28 | −.14 | −.06 | −.02 |
a
Markers from the 10-cM genomewide scan are in bold italics.
b
Genetic distances were deduced from the Marshfield (Center for Medical Genetics) sex-averaged linkage map.
c
pRR8 is located in AC010973.6 starting at nt 93259, pRR10 in AC078834.5 at nt 132119, and pRR15 in AC005534.2 at nt 148849. The number of different alleles observed within family 1270 was three for pRR10, four for pRR8, and five for pRR15.
d
Selected from the genetic map of the Cooperative Human Linkage Center.